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prostanoid br In after the publication of a randomised contr
2019-04-29

In 2012, after the publication of a randomised controlled trial showing that a single oral dose of azithromycin was as effective as intramuscular benzathine benzylpenicillin for the treatment of yaws, WHO launched a new, ambitious initiative—the Morges strategy—for the eradication of the disease b
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The patient s pancytopenia worsened over the ensuing
2019-04-29

The patient׳s pancytopenia worsened over the ensuing weeks and follow-up bone marrow biopsy revealed a marrow that was 75% cellular with 15% dysplastic myeloblasts aberrantly expressing CD7, 23% dysplastic monocytes, and 5% eosinophils. Cytogenetics showed normal male karyotype. FISH was negative fo
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The exact mechanism of bone breakdown is not fully understoo
2019-04-29

The exact mechanism of bone breakdown is not fully understood in lung cancer. However, it is likely similar to what has been observed in bone metastases arising from other tumour types. Bone breakdown, or osteolysis, results from a disruption of the normal balance of bone resorption and formation co
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M s all de la tiran a de
2019-04-29

Más allá de la tiranía de las vanidades, existían sólidos argumentos que justificaban el alejamiento de Paz con respecto pyruvate dehydrogenase kinase la poesía y la persona de Neruda. Con leve antelación a sus contemporáneos chilenos, Octavio Paz resaltaba dos principales defectos en la producción
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In the Governments of Bangladesh
2019-04-29

In 2005, the Governments of Bangladesh, India, and Nepal committed to eliminate visceral leishmaniasis by 2015. The elimination strategy included the prompt treatment of cases with oral miltefosine. This drug was the only realistic option at the time, despite its potential teratogenicity, risk of no
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A esa primera caracter stica se
2019-04-29

A esa primera característica se suma el tema del libro: la lucha armada en la Sierra de las Minas durante los años sesenta. La historiografía sobre la lucha armada en Guatemala, y también en el resto de América Latina, suele ser contradictoria. Al fragor de las expectativas inflamadas por el triunfo
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br Comments The present two cases developed ACC during chemo
2019-04-29

Comments The present two cases developed ACC during chemotherapy induced neutropenic for AML. ACC is a relatively rare complication in these patients’ population. It’s reported in 0.4% among all neutropenic episodes of patients with acute leukemia or aggressive lymphoma undergoing myelosuppressiv
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In the days before Christmas adverse weather conditions and
2019-04-29

In the days before Christmas, 1952, adverse weather conditions and the burning of sulphurous coal led to the death of almost 12 000 people in London. Despite improvements in pollution prevention since the “Great Smog”, London continues to experience toxic air pollution linked to thousands of prematu
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Both typhus and typhoid most
2019-04-29

Both typhus and typhoid most commonly present as undifferentiated febrile illness, defined as fever with no localising features, but have different modes of transmission. Typhoid is transmitted faecal-orally, and typhus is primarily transmitted through insect or mite bites on the skin. is the main
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Thomas Hoeksema por su parte explica
2019-04-28

Thomas Hoeksema, por su parte, explica la paradoja del título del siguiente modo: “la destrucción (fuego) está moderada por la estabilidad y la armonía (reposo). La relación entre estas dos fuerzas es multidimensional y dialéctica”. Para Hoeksema, el segundo volumen poético de Pacheco se debe entend
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ginsenoside rh2 In the current study we
2019-04-28

In the current study, we first isolated primary HSCs from rat liver and then treated the ginsenoside rh2 with alcohol. As shown in Fig. 1, the mRNA levels of PCBP2 and type I collagen were increased significantly. In addition, the type I collagen mRNA level was more significantly increased in prima
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Pero todo cambia despu s
2019-04-28

Pero todo cambia después del exilio en Francia; son los presuntos “bárbaros” los únicos que parecen ser capaces de una auténtica revolución: dirá Bilbao con admiración que ellos fueron los que en 1848 hicieron transporters las “naciones de Europa […] estremecerse como bajo las plantas de Attila”. Lo
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Sorafenib br Potential therapeutic use of PI
2019-04-28

Potential therapeutic use of PI3Kα and/or pan-PI3K inhibitors in CLL PI3Kδ has been the overwhelming target of choice for PI3K inhibition in CLL; however there is mounting evidence for important roles of other PI3K isoforms in CLL and of functional redundancy between PI3K isoforms in leucocytes i
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In the s systematic case detection and treatment campaigns
2019-04-28

In the 1960s, systematic case detection and treatment campaigns brought the disease under control, with fewer than 5000 cases reported per year. However, the political instability and conflicts of the FH535 Supplier following decolonisation in countries such as DR Congo, Angola, and Sudan led to th
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Intrahepatic cholangiocarcinoma ICC originates from the
2019-04-28

Intrahepatic cholangiocarcinoma (ICC) originates from the small intrahepatic ductules or the large intrahepatic ducts proximal to the bifurcation of the right and left hepatic ducts. ICC is the second most common primary malignancy of the liver after hepatocellular carcinoma (HCC). Given the rising
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