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PPCL were associated with a very
2019-05-29
PPCL were associated with a very poor prognosis. The median survival duration according to published small trials was short, ranging from 7 to 13 months, with less than 10% of patients having a median survival of more than 5 years. In the largest recently published epidemiological study, the median
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br Conflict of interest statement br
2019-05-29
Conflict of interest statement Acknowledgments The authors would like to thank Dr. Bjørn Naume, and Dr. Erik Løkkevik from the Department of Clinical Oncology, the Norwegian Radium Hospital for their helpful comments. This study was supported by grants from the Norwegian Radium Hospital Founda
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E 64 br Materials and methods br Results br Discussion
2019-05-29
Materials and methods Results Discussion Utilizing IHC, the majority of OS samples were positive for RANKL (68%), with RANKL staining detectable in OS tumor E 64 and tumor anaplastic cells. However, a wide range of RANKL expression within the OS component was observed and many samples had l
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br Conclusions br Limitation br Acknowledgments
2019-05-29
Conclusions Limitation Acknowledgments This research was supported in part by the China Postdoctoral Science Foundation (Nos. 2013M542478 and 2015T81139), a Grant (no. 2014FB059) from the Joint Special Funds for the Department of Science and Technology of Yunnan Province-Kunming Medical Uni
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Causative genes for ARVC and their respective characteristic
2019-05-29
Causative genes for ARVC and their respective characteristics are summarized in Table 1. Desmosome genes for ARVC Other causative genes for ARVC Although more than half of ARVC patients carry mutations in desmosome genes, other genes have also been reported as causative genes for ARVC (Table
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br La poes a temprana
2019-05-28
La poesía temprana de Carlos Pellicer (1899–1977) ejemplifica un cambio fundamental en la lírica hispanoamericana. Su obra revela la transición entre el cosmopolitismo ahistórico y exotista y una nueva poesía de conciencia histórica que no solo retoma la historia y la realidad propias de Hispanoam
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tropisetron br En relaci n con este ltimo tipo
2019-05-28
En relación con este último tipo de poesía, la escéptica, Baldomero Sanín Cano publica el artículo emblemático de la crítica modernista “Núñez, poeta” en 1888 en La Sanción. En este sentido, el crítico colombiano, David Jiménez afirma que este artículo “contiene ya los planteamientos fundamentales
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Dioscin Desde las organizaciones sociales y poblaciones movi
2019-05-28
Desde las organizaciones sociales y poblaciones movilizadas, estas protestas marcan el inicio de un nuevo periodo de distanciamiento frente Dioscin los actores político-institucionales, en particular el Partido Nacionalista que logró aglutinar electoralmente sus críticas y expectativas de cambio fre
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Sendo o propositor da lei
2019-05-28
Sendo o propositor da lei das os, Bresser Pereira as definiu como entidades sem fim lucrativo, públicas não estatais, financiadas pelo Estado e por ele controladas através de contrato de gestão com fxação de indicadores de desempenho. Dessa forma proporcionariam maior autonomia e flexibilidade das a
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En estos trabajos la referencia a
2019-05-28
En estos trabajos la referencia Mifepristone la obra de Ernesto Laclau es una constante, que a su vez es marginal. Casi todos los estudios lo citan como un antecedente en ese lugar común que se transformó el referir a la polisemia del concepto y es difícil considerar un estado de la cuestión sin su
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Heart failure is a complex disease and
2019-05-28
Heart failure is a complex disease and the status of each patient is highly heterogeneous; therefore, nominal manufacturer-delivered device settings may not be optimal for all patients who receive CRT implantation. A growing body of evidence suggests hemodynamic and clinical status benefits associat
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br Material and methods The study subjects
2019-05-28
Material and methods The study subjects were 28 consecutive patients with organic BV6 disease who underwent ICD implantation for the secondary prevention of sudden cardiac death, based on the indications for ICD implantation in the European Society of Cardiology׳s guidelines [12]. The reason for
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Introduction Researchers have long followed the strategy tha
2019-05-28
Introduction Researchers have long followed the strategy that in order to achieve a fuller understanding of the causes of disease and how they can be prevented, it is necessary to study the biochemical and physiological processes involved in the etiology of disease. As I have argued in previous pap
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Introduction Bone is a very dynamic tissue resulting from co
2019-05-28
Introduction Bone is a very dynamic tissue resulting from coordinated phases of formation and resorption called bone remodelling. Additional to its role in phosphocalcic homoeostasis, bone remodelling process is necessary for bone growth, for renewal of cellular and extracellular matrix components
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MDV 3100 Aside from distinct technical approaches used
2019-05-28
Aside from distinct technical approaches used, the well-established RANKL and RANK expression patterns in the bone further substantiates the expression patterns defined in the current study of OS. RANKL and RANK play major roles in bone metabolism due to the critical role of this pathway in osteocla
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