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Preventive chemotherapy for schistosomiasis is rapidly scali
2019-06-24

Preventive chemotherapy for schistosomiasis is rapidly scaling up worldwide. The global coverage that was less than 10% in 2010 is now higher than 30%, however, the main limitation for the scaling up is the availability of donated drug. In school age children, the age group for which praziquantel is
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br Bisphosphonate use and breast cancer risk
2019-06-24

Bisphosphonate use and breast cancer risk BPs are commonly used in the management of postmenopausal osteoporosis. They consist of two phosphate groups, which give them a high affinity to bone. They attach to bone at exposed calcium hydroxyapatite binding sites, which are most accessible at sites
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Dexmedetomidine HCl of Despite our best efforts the cause of
2019-06-24

Despite our best efforts, the cause of SCD in young individuals is sometimes not established; no cause is identified in up to 40% of cases. Importantly, whether a cause of death is established or not, the possibility of an underlying inherited cardiac disorder remains in many cases, including the po
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Hasta el tercer acto cuando Licurgo se casa y
2019-06-24

Hasta el tercer acto, cuando Licurgo se casa y vuelve proton pump inhibitor la racionalidad, presenta al Rey una serie de leyes, quien, sin conocerlas, le pregunta si desea hacerlas públicas, pero, desde otra óptica, Licurgo responde: Son, pues, el Rey y el Reino quienes deben acordar las leyes, pa
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En relaci n con lo anterior
2019-06-24

En relación con lo anterior, el papel de los medios de comunicación en la vigilancia de los asuntos del Estado, Bentham defendía la importancia de hacer públicas las sesiones del Congreso, así como el ataque frontal al secretismo de los gobernantes tradicionales. Es decir, era evidente que para el f
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Es as como se establece la relaci
2019-06-24

Es así como se establece la relación entre los dos relatos: la novela histórica es parte de la novela policíaca y ambas tienden al mismo fin trágico, la muerte de su respectivo héroe. Al respecto, conviene hacer ciertas acotaciones sobre el término de “héroe”. Si bien en este último pasaje citado de
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Second governments can play an
2019-06-24

Second, governments can play an important part in providing incentives for industry to invest in discovering new uses for old drugs. For example, it ZM 447439 could consider the extension of patent protection for old drugs that have found new uses, for example, as embodied in the Hatch-Waxman Act in
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One of the unheralded developments in global
2019-06-24

One of the unheralded developments in global health is the welcome increase in the number of older people (ie, aged 60 or 65 years and older) in low-income and middle-income countries. In parallel with the gains from this longevity dividend, ageing presents particular challenges to health services.
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Methylcobalamin LQTS is classified into subtypes LQT to LQT
2019-06-21

LQTS is classified into subtypes LQT1 to LQT13 based on the site of genetic mutation. Each type possesses distinct clinical characteristics and a different prognosis. Treatment choice depends partly on individual phenotype and partly on genotype. Among Asian countries, several reports have been publ
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Mechanistic target of rapamycin mTOR a highly
2019-06-21

Mechanistic target of rapamycin (mTOR), a highly conserved serine-threonine protein kinase, is a key regulator of cell growth and metabolism. As discussed above, mTORC1 is a negative regulator of the preinitiation complex that modulates the initiation of autophagosome biogenesis. Pharmacological and
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In Grabowski and colleagues report
2019-06-21

In , Grabowski and colleagues report that women consistently using DMPA were at nearly double the risk of acquiring herpes simplex virus type 2 (HSV2) compared with those using no contraception; in a sensitivity analysis limited to those whose main partner had HSV2, the risk increased by six times.
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The other uncommon types of idiopathic VT
2019-06-21

The other uncommon types of idiopathic VT such as non-reentrant focal Purkinje VT, papillary muscle VT, and mitral/tricuspid annular VT may also present as incessant or repetitive forms of monomorphic VT. Importantly, an incessant nature of the VTs can secondarily decrease the global (not segmental)
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br Discussion The cardiac manifestations of organophosphorus
2019-06-21

Discussion The cardiac manifestations of organophosphorus poisoning are well known, involving various electrocardiographic abnormalities that may range from sinus tachycardia to ST elevation. Such most common abnormalities are sinus bradycardia, prolonged QT interval, and ST elevation [2–4]. Most
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In addition to inducing IKs
2019-06-21

In addition to inducing IKs dysfunction through dominant-negative loss-of-function effects and defective channel trafficking, mutations in KCNQ1 suppress IKs channel function by reducing the channel affinity of interacting proteins [68,69]. Phosphatidylinositol-4,5-bisphosphate (PIP2) is a cofactor
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Sea una domesticaci n retraducci n simplificaci n o reversi
2019-06-21

Sea una domesticación, retraducción, simplificación o reversión del francés al español del Caribe, lo cierto es que estos traductores se benefician del discurso literario utilizado por Chateaubriand ya que se muestra como un discurso flexible, capaz de aceptar cambios, desvíos y apropiaciones. En At
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