• br Prior to Zika virus infection was described as a

  2019-06-28

  

  Prior to 2013–14, Zika virus infection was described as a mild febrile illness with clinical symptoms. However, the emergence of Zika virus in the Pacific and the Americas, the sharp increase in cases of Guillain-Barré syndrome (GBS), and the birth of babies with neurological complications such as

• br Conclusion br Conflict of interest statement br Authors c

  2019-06-28

  

  Conclusion Conflict of interest statement Authors\' contribution Introduction There are two classes of bisphosphonates that differ with regard to structure and mechanism of action [1]. The first one includes pyrophosphate-resembling bisphosphonates, such as clodronate and etidronate, whi

• The osteoid and woven bone can be seen as

  2019-06-28

  

  The osteoid and woven bone can be seen as interconnected trabeculae (thin or broad) or sheets. The bone surrounding the lesion (host bone) is strong and is made of varying mixtures of woven and lamellar bone [36]. The radiologic appearance of cortical osteoid osteoma arising in the shaft of a long b

• Myeloid sarcoma can be observed as a de

  2019-06-28

  

  Myeloid sarcoma can be observed as a de novo malignancy (without leukemic presentation in peripheral blood and bone marrow), during the course of acute myeloid leukemia (AML), affecting 2.5–9% of all AML patients, myelodysplastic syndromes (MDS) or myeloproliferative neoplasms (MPNs, both chronic my

• T wave alternans is a periodic beat to beat

  2019-06-28

  

  T-wave alternans is a periodic beat-to-beat variation in the amplitude or morphology of the T wave on electrocardiography (ECG) (Fig. 1). Beat-to-beat T-wave alternans is considered to reflect increased dispersion of ventricular repolarization, and it is known to often precede the development of let

• As shown in Table of those women in

  2019-06-28

  

  As shown in Table 3, 55% of those women in the 20–29 years old category had high knowledge regarding cervical cancer screening. Also, 55% of the Shona and 50% of the Ndebele had high knowledge of cervical cancer screening. Additionally, 55% of the married women and 67% of the widowed women had high

• The effects of zoledronic acid are most

  2019-06-28

  

  The effects of zoledronic IRAK inhibitor 6 are most likely due to impairment of the tumour-driven alterations to the bone microenvironment. This may render the bone marrow cavity unfavourable for metastatic growth, potentially redirecting tumour cells to other sites, including the periosteal surface

• RANK RANKL The RANK RANKL signaling pathway is a

  2019-06-28

  

  RANK/RANKL: The RANK/RANKL signaling pathway is a critical component of both normal and malignant bone remodeling. RANK is a transmembrane signaling receptor and a member of the tumor necrosis receptor (TNF) superfamily that is found on the surface of OCL precursors [43,44]. RANK ligand (RANKL) is e

• br Conflict of interest statement br Acknowledgments Funded

  2019-06-28

  

  Conflict of interest statement Acknowledgments Funded by the Division of Medical Oncology at Princess Margaret Hospital, Toronto, Canada. No pharmaceutical company funding was received. The authors acknowledge the roles of Esther Lee and Tazmin Usmani in trial coordination and Dr. Ranjeeta Mal

• In this study we applied a more general approach

  2019-06-28

  

  In this study, we applied a more general approach along these lines, which has previously been used only in few reports in the literature [8]. Based on a prospective BC database including all newly diagnosed BC cases at a large Swiss breast center over a 20-year period, we aimed to give a comprehens

• NG25 of br Conclusion br Conflict of interest This

  2019-06-28

  

  Conclusion Conflict of interest This work was supported by Medtronic Japan. MN received honoraria from Medtronic Japan, St. Jude Medical Japan and Boston Scientific Japan. YE and TI received honoraria from Medtronic Japan. HS received honoraria from Japan Lifeline. YA, TT, and KK are employees

• br Discussion IUI with controlled ovarian hyperstimulation h

  2019-06-27

  

  Discussion IUI with controlled ovarian hyperstimulation has been used over the years as a treatment for mild male factor, anovulation, and unexplained infertility. It is less expensive and less invasive than other assisted reproductive techniques. Therefore, these advantages have made the techniq

• br Conflict of interest br Introduction Antiarrhythmic devic

  2019-06-27

  

  Conflict of interest Introduction Antiarrhythmic device lead implantation using the cephalic vein (CV) cutdown technique is considered to be superior to the conventional subclavian vein puncture method with regards to the incidence of perioperative complications such as pneumothorax [1,2] and

• TMP269 weight Therefore it is necessary to identify

  2019-06-27

  

  Therefore, it is necessary to identify the accuracy of ECG in predicting a spontaneous syncope. Some waterproof Holter ECGs are commercially available; however, their use is not yet widespread. Moreover, patients may not experience syncope symptoms during the recording period. Given that the ILR can

• This patient s shortest R R interval

  2019-06-27

  

  This patient\'s shortest R–R interval on ECG was about 200ms (300bpm), which indicated high risk of sudden cardiac death. The patient underwent catheter ablation. ACC/AHA/ESC guidelines for the management of patients with supraventricular arrhythmias [1], which include accessory pathway-mediated arr

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