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This time last year to coincide with March launched a
2019-06-12
This time last year, to coincide with (March 9), launched a to highlight the rising burden of kidney disease and to encourage research partnerships to address gaps in knowledge and care, including the affordability of such care. Nephrology research and collaboration has come a relatively long way
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Two other groups subsequently published further data on
2019-06-12
Two other groups subsequently published further data on iPSCs models of ARVC that have improved our understanding of this disease. Kim et al. developed iPSC models using episomal methods from 2 ARVC patients, as well as with PKP2 mutations . Detailed electrophysiological characterization of mutant
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Regarding the pathophysiology of HF with preserved LVEF
2019-06-12
Regarding the pathophysiology of HF with preserved LVEF, AF is one of the most important precipitating factors related to diastolic dysfunction [22,23]. AF might have important roles in the pathogenesis of HF with preserved EF in association with diastolic HF. Compared with JCARE-CARD, which include
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A year old male was referred
2019-06-12
A 59-year-old male was referred to our hospital in cardiogenic shock. A 12-lead electrocardiogram showed abnormal Q-waves in V1–V4 leads and complete atrioventricular block; the patient was diagnosed with acute myocardial infarction (AMI) (Fig. 1). Upon arrival, the patient was unconscious, and his
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indole-3-carbinol br Conclusion br Conflict of interest br
2019-06-12
Conclusion Conflict of interest Introduction Radiofrequency catheter ablation has been established as an effective and curative therapy for Wolff-Parkinson-White Syndrome [1–4]. Therefore, prediction of the precise location of an accessory pathway (AP) prior to the ablation procedure is of
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In bone microenvironment OPG RANK RANKL molecular triad
2019-06-12
In bone microenvironment, OPG/RANK/RANKL molecular triad is not solely expressed by bone cells. Whether OPG is considered as a ubiquitary receptor [20], membrane RANK is expressed by various tumour phosphodiesterase inhibitor that originate from primary bone tumours or bone metastases, from mesench
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Al cronista cinematogr fico le toc cubrir la etapa
2019-06-12
Al cronista cinematográfico le tocó cubrir la etapa denominada “preindus-trial”, en relación flt3 la que después se le conocería como “época de oro” del cine mexicano, cuyos prolegómenos se identifican a partir de 1936 con el éxito internacional de , de Fernando de Fuentes, se afianza la fase durant
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En su primera entrega para en la pantalla de septiembre
2019-06-12
En su primera entrega para “ en la pantalla” (3 de septiembre) Luis Cardoza establece matizadamente los parámetros sobre “la crítica” y lo que para él representa la cinematografía como expresión estética; los lineamientos observados de antemano explican sus continuas confrontaciones con el medio. Pu
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Ideally assessment of obstetric interventions and
2019-06-12
Ideally, assessment of obstetric interventions and outcomes should be based on high-quality, recent data from the entire population or a representative sample. A key feature of the Robson classification is that it uses information that is available at the onset of labour or delivery, is routinely co
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It means an opportunity As
2019-06-12
It means an opportunity. As we concern ourselves with the prominence of health in the new agenda, it\'s easy to forget that (human) development is by definition people-centred, and that living a long, healthy, and creative life is its cornerstone. The expansion of the new goals to encompass many (if
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br The introduction of direct acting
2019-06-12
The introduction of direct-acting antiviral drugs (DAAs) is changing the treatment options for hepatitis C ras inhibitor (HCV). These new medicines were initially marketed at a very high price, but several countries have negotiated favourable price reductions, and, in view of the low cost of prod
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Pero m s all del folclore la conmemoraci n
2019-06-12
Pero más allá del folclore, la conmemoración, con su ampulosidad y minucia, debía servir para medir la destreza virtuosa de los participantes, al exigir cierta competencia en la observancia de sus enigmas por parte de nuevos cristianos “ya bien enseñados en la Fe” (nos dice también Ávila) tras haber
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Several true lumen re entry
2019-06-11
Several true lumen re-entry devices have been introduced into the market, including the Outback catheter, allowing fluoroscopically controlled true arterial lumen re-entry after subintimal guidewire passage. A recent retrospective review reported a successful re-entry rate of 91% in 11 patients with
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br The L type calcium channel LTCC
2019-06-11
The L-type calcium channel (LTCC) in heart consists of 4 subunits: α1, β2, α2, and δ [47], encoded by CACNA1C, CACNB2, and CACNA2D, respectively, with the α2 and δ subunits encoded by the gene CANA2D. In 2007, Antzelevitch et al. [48] reported 2 CACNA1C mutations and a CACNB2 mutation from a genot
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order azidothymidine Both breast cancer and MM cause osteoly
2019-06-11
Both breast cancer and MM cause osteolytic lesions, inhibiting osteoblast differentiation and thereby tipping the balance in favour of osteoclastic activity. In contrast, prostate cancer predominantly causes osteoblastic bone disease. Interestingly, increased marrow adiposity has been associated wit
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